)

). [PubMed] [Google Scholar] 9. express TA02 at all. A few cases of renal cell cancer, pancreatic cancer, breast cancer, thyroid cancer, colon cancer and ovarian cancer showed low expression, but the staining patterns were completely different from that of primary lung adenocarcinoma, which showed a granular staining pattern. Our novel mAbs should be valuable for immunochemical detection of TA02/napsin A. strong class=”kwd-title” Keywords: TA02, napsin A, monoclonal antibody against TA02, human aspartic proteinase, primary lung adenocarcinoma REFERENCES 1. ) Shimosato , Y.Pulmonary neoplasm . em In /em Diagnostic Surgical Pathology, 2nd Ed. , ed. Sternberg S. S. , pp. 1045 C 1093 ( 1994. ). Raven Press; , New York . [Google Scholar] 2. ) Hirano , T. , Franzen , B. , Uryu , K. , Okuzawa , K. , Alaiya , A. A. , Vanky , F. , Rodrigues , Y. , Ebihara , Y. , Kato , H. and Auer , G.Detection of polypeptides associated with the histopathological differentiation of primary lung carcinoma . Br. J. Cancer , 72 , 840 C 848 ( 1995. ). [PMC free article] [PubMed] [Google Scholar] 3. ) Hirano , T. , Fujioka , K. , Franzen , B. , Okuzawa , K. , Uryu , K. , Shibanuma , H. , Numata , K. , Konaka , C. , Ebihara , Y. , Takahashi , M. , Kato , H. and Auer Avatrombopag , G.Relationship between TA01 and TA02 polypeptides associated with lung adenocarcinoma and histocytological features . Br. J. Cancer , 75 , 978 C 985 ( 1997. ). [PMC free article] [PubMed] [Google Scholar] 4. ) Tannell , P. J. , Powell , D. J. , Hill , J. , Smith , T. S. , Tew , D. G. and Kay , J.Napsins: new human aspartic proteinases. Distinction between two closely related genes . FEBS Lett. , 441 , 43 C 48 ( 1998. ). [PubMed] [Google Scholar] 5. ) Franzen , B. , Okuzawa , K. , Linder , S. , Kato , H. and Auer , G.Non\enzymatic extraction of cells from clinical tumor material for analysis of gene expression by two\dimensional polyacrylamide gel electrophoresis . Electrophoresis , 14 , 1045 C 1053 ( 1993. ). [PubMed] [Google Scholar] 6. ) Okuzawa , Avatrombopag K. , Franzen , B. , Lindholm , J. , Linder , S. , Hirano , T. , Bergman , T. , Ebihara , Y. , Kato , H. and Auer , G.Characterization of gene expression in clinical lung cancer material by two\dimensional polyacrylamide gel electrophoresis . Electrophoresis , 15 , 382 C 390 ( 1994. ). [PubMed] Avatrombopag [Google Scholar] 7. ) Banno , S. , Yoshikawa , K. , Nakamura , S. , Yamamoto , K. , Seito , T. , Nitta , M. , Takahashi , T. , Ueda , R. and Seto , M.Monoclonal antibody against PRAD1/cyclin D1 stains nuclei of tumor cells with translocation or amplification at em BCL\1 locus /em . Jpn. J. Cancer Res. , 85 , 918 C 926 ( 1994. ). [PMC free article] [PubMed] [Google Scholar] 8. ) Laemmli , U. K.Cleavage of structural proteins during the assembly of the head of bacteriophage T4 . Nature , 227 , 680 C 685 ( 1970. ). [PubMed] [Google Scholar] 9. ) Chuman , Y. , Bergman , A. , Ueno , T. , Saito , S. , Sakaguchi , K. , Alaiya FGF20 , A. , Franzen , B. , Bergman , T. , Arnott , D. , Auer , G. , Appella , E. , Jornvell , H. and Linder , S.Napsin A, a member of the aspartic protease family, is abundantly expressed in Avatrombopag normal lung and kidney tissue and is expressed in lung adenocarcinomas . FEBS Lett. , 462 , 129 C 134 ( 1999. ). [PubMed] [Google Scholar] 10. ) Auten , R..